In this lecture, the bivariate twin model is extended to the multivariate twin model. It is explained how the variance in four traits is decomposed into additive genetic, non-additive genetic, and ...

The neurotoxic effects of chemical agents are often investigated in controlled studies on rodents, with multiple binary and continuous endpoints routinely collected. One goal is to conduct ...

In this lecture, the univariate twin model is extended to the bivariate twin model. It is explained how the variance in two traits is decomposed into additive genetic, non-additive genetic, and ...

It can be more challenging to efficiently model the covariance matrices for multivariate longitudinal data than for the univariate case, due to the correlations arising between multiple responses. The ...