A deficiency of one or more components of the prothrombin complex may complicate many clinical states: cirrhosis; hepatitis; biliary obstruction; malabsorption; childbirth; and the preoperative and ...

How did eukaryotic organisms become so much more complex than prokaryotic ones, without a whole lot more genes? The answer lies in transcription factors. Experiments have shown that TFs can bind ...

To understand the pharmacology and mechanism of action of ximelagatran, a review of the formation and function of thrombin is warranted. [10] The generation of thrombin is limited under normal ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 70, No. 2 (Feb., 1973), pp. 310-314 (5 pages) One pathway of blood coagulation, the extrinsic system, is initiated ...