Baylor College of Medicine will be a site for a new multi-institution project aimed at investigating preclinical drug safety ...

Developing new drugs is one of the riskiest and most expensive endeavors in science. Today, The Jackson Laboratory (JAX) ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Parallel Bio, a biotech company pioneering human-first drug discovery, today announced it has raised $21 million Series A funding, led by AIX Ventures. The round ...

In the UK, there was a case where TGN1412, an immunotherapy under development, triggered a cytokine storm within hours of administration to humans, leading to multiple organ failure. Another example, ...

From idea, to lab, to clinic, to approval—it's a long and expensive process to bring a drug to market. It also rarely succeeds. Northeastern University researchers You Wu and Lei Xie are proposing ...

For decades, animal models have been the gold standard for preclinical testing of potential drugs. Yet, even the best animal models are not perfect. For example, small rodent species with engrafted ...

Organoid-on-chip technology merges patient-derived organoids with microfluidic engineering to recreate human physiology and predict drug responses with high precision. This innovation is reshaping ...

Genetically-humanized FcRn mice provide translational pharmacokinetics (PK) and pharmacodynamics (PD) data for antibody-based therapeutics. The image illustrates a therapeutic antibody (blue) adhering ...

In the UK, there was a case where TGN1412, an immunotherapy under development, triggered a cytokine storm within hours of administration to humans, leading to multiple organ failure. Another example, ...

The Food and Drug Administration and National Institutes of Health held a joint workshop July 7 on reducing animal testing in research, strikingly announcing that “NIH will no longer seek proposals ...

Organoids, organs-on-a-chip, and machine learning technologies have improved dramatically in recent years, but have they come far enough to replace animal research? Additionally, despite attempts to ...